Display.
Ergonomics.
Inputs.
App interactions.
System features.
Best practices
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Take advantage of the large display to elevate the content people care about, minimizing modal interfaces and full-screen transitions, and positioning onscreen controls where they’re easy to reach, but not in the way.
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Use viewing distance and input mode to help you determine the size and density of the onscreen content you display.
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Let people use Multi-Touch gestures, a physical keyboard or trackpad, or Apple Pencil, and consider supporting unique interactions that combine multiple input modes.
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Adapt seamlessly to appearance changes — like device orientation, multitasking modes, Dark Mode, and Dynamic Type — and transition effortlessly to running in macOS, letting people choose the configurations that work best for them.
For the complete guidance, including worked examples and illustrations, see the canonical page: https://developer.apple.com/design/human-interface-guidelines/designing-for-ipados